Playing a minor 12-bar blues? Not so bad.
Playing it in C# minor (concert)? Not so good.
Playing it to make Coltrane proud? Well ...
Coltrane's "Equinox" is a simple 12-bar blues. Everybody can play the head, even in C# minor with a little practice. But this is a very uncomfortable key for most wind players, so plan to take some time to get the brain and fingers working in this key to open up the improvisation possibilities.